FIGURE 5

FIGURE 5

Telomerase depletion accelerates ageing‐assoicated increase in anxiety‐like behaviour. (A) Schematic figure of the setup and behaviour assessment during the novel tank test (NTT). (B) Quantifications show that old WT (30–36 months) spend less periods of time in the top part of the tank compared to younger siblings, and that this behaviour is accelerated in tert^−/− from the age of 2–6 months. (C) Quantifications of the total distance swam during the entirety of the test show no differences between groups, suggesting that the differences observed in the time spent in the top area of the tank are not explained by locomotive defects. N = 10–14. Each dot represents a fish. Bar errors represent the SEM. *p < 0.05; ***p < 0.001.