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Fig. 6 Terminal differentiation of PRs is defective. (A) Heatmap showing the top downregulated genes of the Phototransduction Term. The bar shows the average FPKM value of three replicates. Yellow color indicates a high expression level, and black color indicates a low expression level. Genes are organized according to their Padj value from small to large (range 3.8–64 to 0.00749). (B) Confocal sections of 5 dpf Ctrl and smarce1-/- retinas stained with the Zpr1 antibody (green). Ectopic cones are visible in inner locations (yellow arrows) in the mutant images. Right lower panel shows a closer caption of the PRs where disorganization can be appreciated. Scale bars, upper panel:40 μm; left lower panel: 20 μm; right lower panel: 10 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)