ZFIN Image: Farr et al., 2025, Fig 5

Image

Figure Caption

Fig 5 Early heart development appears normal in pomp and psmd6 mutants.

A.-C. Dorsal views of ALPM labeled for myl7 in blue in 18 hpf embryos. Normal heart morphology: 6/6 pomp⁺^/⁺, 7/7 psmd6⁺^/⁺, 11/11 pomp^-/-, 8/8 psmd6^-/-. Scale bar = 100 μm. D.-F. Dorsal views of hearts labeled for myl7 in blue in 24 hpf larvae. Normal heart morphology: 8/8 pomp⁺^/⁺, 8/8 psmd6⁺^/⁺, 6/6 pomp^-/-, 10/10 psmd6^-/-. Scale bar = 100 μm. G.-I. Ventral views of hearts labeled with myl7:EGFP in 48 hpf embryos. Normal heart morphology: 13/16 pomp⁺^/⁺, 11/12 psmd6⁺^/⁺, 14/14 pomp^-/-, 11/12 psmd6^-/-. Scale bar = 50 μm. V, ventricle. A, atrium. J.-L. Ventral views of hearts labeled with myl7:EGFP in 72 hpf larvae. Normal heart morphology: 35/38 pomp⁺^/⁺, 22/24 psmd6⁺^/⁺, 39/45 pomp^-/-, 25/29 psmd6^-/-. All embryos were genotyped. Scale bar = 50 μm. V, ventricle. A, atrium.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.