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Fig. 6 Effect of RDM on dopaminergic-specific marker TH, GRP78, and BCL2 expression in 6-OHDA-induced zebrafish PD models. The zebrafish heads were collected, and TH levels were measured using Western blot, while mRNA levels of GRP78 and BCL2 were measured using RT-PCR. The protein level of (A) TH was analyzed using β-actin as the internal control. mRNA levels of (B) GRP78 and BCL2 were analyzed by using GAPDH as the internal control. The relative protein expression level of control zebrafish is presented as 100% for normalization. *p < 0.05 compared with the control group; #p < 0.05 compared with the 6-OHDA alone group. 6-OHDA, 6-hydroxydopamine; RDM, rhodoptilometrin; RT-PCR, real-time polymerase chain reaction; and TH, tyrosine hydroxylase.