Improved effect of epicoccin A on MPTP-induced locomotor impairment in zebrafish. (A) Four representative movement trajectories of zebrafish from control, MPTP, rasagiline, and epicoccin A plus MPTP co-treatments, n = 22. Red, green, and black lines represent fast (>0.5 cm/s), medium (0.2–0.5 cm/s), and slow (<0.2 cm/s) movement trajectories, respectively. (B) The total distance moved by zebrafish, n = 22. (C) Average speed was calculated at every 60 s interval within the 20 min recording period for all individuals from each group, n = 22. The data are presented as the mean ± SEM; ####p < 0.0001 compared to the control group; ** p < 0.01 and *** p < 0.001 compared to the MPTP group.
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