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Fig. 3 In vitro validation of L. plantarum APC2688 potential to degrade candidate prebiotics of different complexities while producing neuroactive molecules involved in stress modulation. (A) Growth curves of L plantarum APC2688 when growing in different media. An N of three was used for each growth media. (B), (C) and (D) represent the CLR-transformed abundance of GABA, acetate and tryptophan in the cell-free supernatants of APC2688, respectively. An N of three was used for each growth medium. Differences between groups were tested by one-way ANOVA. Stars represent contrasts with adjusted p values below 0.05. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, and ****p ≤ 0.0001. Only statistically significant results are shown.