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Fig. 3 cdk1 mutation leads to the production of polyploid and aneuploid zebrafish. A Chromosome spreads of cells of 24-hpf embryos of WT zebrafish. Scale bar = 5 µm. B Chromosome spreads of cells of 24-hpf embryos of WT ♀ × cdk1+/− ♂ zebrafish. Scale bar = 5 µm. C Ploidy detection of 24-hpf embryos of WT zebrafish. D Ploidy detection of 24-hpf embryos of WT ♀ × cdk1+/− ♂ zebrafish. cdk1, cyclin-dependent kinase 1; WT, wild-type zebrafish; cdk1+/−, zebrafish with heterozygous mutation of cdk1; hpf, hour post fertilization; n, number; 2N, diploid; 3N, triploid; 3N + , hypertriploid; 5N, pentaploid; ♀, female; ♂, male