FIGURE 3

FIGURE 3

Matrix metalloproteinase (MMP)‐2 upregulation in the dorsal aorta of angiotensin II (AngII)‐injected zebrafish. Representative Masson's trichrome, Picrosirius red, and Alcian blue‐stained (a), immunohistochemically stained with anti‐procollagen type I, aggrecan, and L‐plastin antibodies (b) of the transverse sections taken from the segments v1/v2 of the dorsal aorta in control and 160 ng AngII‐injected Tg(kdrl:EGFP) zebrafish at 8 wpf. (c) Representative immunohistochemically stained with anti‐MMP‐2 antibody of the transverse sections taken from the rostral (v1 or v2) and caudal (v4) segments of the dorsal aorta in control and 160 ng AngII‐injected Tg(kdrl:EGFP) zebrafish at 8 wpf. Arrowheads indicate the dorsal aorta. Scale bars: 50 μm.