Potential miRNA-mRNA interacted pairs involved in nervous system development. A The workflow of screening miRNA-mRNA interacted pairs. B Functional enrichment analysis of predicted miRNA targets. C Protein–protein interaction network and densely connected network components (DCNCs). D Potential miRNA regulated genes in DCNCs (M1–M8) visualized with a “synteny”-like plot. Link colors and rectangle colors in up- or down-panel depict DCNC colors in panel C. Highly connected genes in each DCNC were labeled. E Visualization of miRNA-mRNA pairs of the top 20 connected miRNAs and highly connected genes in each DCNC and common miRNAs in regulating two key retinal differential transcription factors, crx and neurod1
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