Fig. 4

Fig. 4

Development-related miRNAs in zebrafish brain. A Expression patterns of differentially expressed miRNAs by pairwise comparisons, expression of miRNAs in adult tissues, as well as the evidence supported by the RNA in situ hybridization experiment. B Volcano plots depict differentially expressed miRNAs in comparison of 48 h vs. 24 h and 96 h vs. 48 h. C Illustration locus of four miRNA clusters. Colors in upper three clusters indicated the expression patterns in Fig. 3a, and gray color indicated miRNAs without differential expression. D RT-qPCR validation of six miRNAs in RNA-seq datasets