ZFIN Image: Lovely, 2024, Fig. 2

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Figure Caption

Fig. 2 Upregulation of GATA3 does not rescue ethanol-induced palate defects in bmp4 mutant larvae. Comparison of palate defects in non-heat shocked control and ethanol-treated bmp4 mutant larvae to heat shocked control and ethanol-treated bmp4 mutant larvae. Ethanol exposure results in over 20 % of palate defects in bmp4 mutant larvae. Heat shock induced, upregulation of GATA3 does not rescue ethanol induced palate defects in bmp4 mutant larvae. Percent of phenotypes were quantified and compared for untreated and ethanol-treated larvae for each Bmp component using (two-way ANOVA, F = 57.77, p < 0.0001; pairwise comparisons **** = p < 0.0001, ** = p < 0.005). “n” for each treatment group listed in Table 4.

Figure Data

Phenotype details

Acknowledgments

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Reprinted from Reproductive toxicology (Elmsford, N.Y.), 131, Lovely, C.B., Bone Morphogenetic Protein signaling pathway - ethanol interactions disrupt palate formation independent of gata3, 108754, Copyright (2024) with permission from Elsevier. Full text @ Reprod. Toxicol.