ZFIN Image: Rostad et al., 2024, Figure 2

Image

Figure Caption

Figure 2

DJ-1-knockout animals show a high degree of degenerating sub-sarcolemma mitochondria in red muscle. Figure shows transmission electron micrographs of red muscle from 18-month-old wild-type (A) and DJ-1-knockout (B,C) zebrafish. Panel B shows examples of healthy (black asterisk) and degenerating (white asterisk) mitochondria found in red muscle. In wild-type red muscle, mitochondria appeared healthy and no degenerating mitochondria were observed in the sub-sarcolemma (A). In the DJ-1 knockout, a high degree of degenerating mitochondria and autophagic structures (arrows) in the sub-sarcolemma were observed (C).

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)