Repeated LSD effect in the open field (OF) test during withdrawal. (A) Time spent in the inner zone was not significantly different during withdrawal OF testing. (B) Time spent in the transition zone was not significantly different during withdrawal OF testing. (C). Time spent in the thigmotaxis zone was not significantly different during withdrawal OF testing. (D) Velocity was not significantly different during the withdrawal OF testing. (E) Meandering was not significantly different during post-dose OF testing. (F) High mobility was not significantly different during withdrawal OF testing. (G). Mobility was not significantly different during withdrawal OF testing. (H) Low mobility was not significantly different during withdrawal OF testing. Sample sizes for A-H: 0 (n = 54), 1.5 (n = 52), 15 (n = 54), 150 (n = 54). Data presented as mean + /- SD.
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