ZFIN Image: Zhang et al., 2023, Fig. 2

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Figure Caption

Fig. 2 Parallel and antiparallel intercellular relationships at the lateral cell membranes of the neural cells change dynamically during neurulation. (A) Interdigitation of the apical protrusions of contralateral neural keel cells (pink and blue) generates the antiparallel orientational relationship between contralateral cells at the interdigitation zone, which is centred at the midline. This region may sense tension of cells. The balancing point of this tension (the spring icon) may automatically define the midline, thus acting as a midline sensor. The basal halves of neural keel cells display a parallel orientational relationship between ipsilateral cells. Corresponding antiparallel orientational cell adhesion (OCAs) and parallel OCAs are expected to exist in these regions that maintain the antiparallel and parallel intercellular relationships, respectively. (B) Plot illustrating that the parallel and antiparallel surface areas will change in opposite directions during the neural plate–keel–rod transition, with 1 representing the total lateral surface area.

Acknowledgments

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