ZFIN Image: Rodríguez-Ruiz et al., 2023, Fig. 8

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Figure Caption

Fig. 8 NLRP1 is activated by phosphorylation of the linker domain after activation of ZAKα A–E Number of neutrophils (A–D), and caspase‐1 activity (E) in 2 dpf larvae obtained by injection of one‐cell stage embryos with human NLRP1 (wild type‐WT, S107A and S107D) and treated from 1 to 2 dpf by bath immersion with 1 μM nilotinib (D, E). Representative images of neutrophils (arrows) are also shown in (C). Each dot represents one individual and the mean ± SEM for each group is also shown. Data are shown as the means ± SEM of two technical replicates in (E). P values were calculated by one‐way ANOVA and Tukey's multiple range test. n.s., non‐significant; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Mol. Med.