ZFIN Image: Deng et al., 2023, Figure 6

Image

Figure Caption

Figure 6

brsk2ab^−/− zebrafish displayed escalating anxiety-like behaviors. (A) The analytical paradigm showed that the open field tank was divided into two equal zones, and the thigmotaxis was calculated using the time and distance ratio that fish spent in the peripheral zone. (B) There was no significant difference in the thigmotaxis index between WT and brska2b⁻^/⁻ zebrafish at 2 mpf (WT vs. brsk2ab^−/−, n = 20: 27, distance: 0.7737 ± 0.14 vs. 0.8376 ± 0.16, p = 0.1622; time: 0.8245 ± 0.13 vs. 0.8712 ± 0.15, p = 0.2225). (C) The thigmotaxis of brsk2ab^−/− zebrafish was observed to have increased more than that of WT zebrafish at 3 mpf (WT vs. brsk2ab^−/−, n = 27: 22, distance: 0.8522 ± 0.05 vs. 0.9274 ± 0.05, p < 0.0001; time: 0.8934 ± 0.05 vs. 0.9389 ± 0.06, p = 0.0038). Data are shown as mean ± SEM s, ** p < 0.01, **** p < 0.0001.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.