|
Fig. 6 Clearance of 80 nm AuNPs (exposed at 2 mg/L) from the pronephros of zebrafish embryo-larvae measured by fluorescence detection with SPIM with the data presented as scatter plots. Fluorescence was measured in both sides of the zebrafish embryo-larvae pronephros and averaged for each individual fish. The same fish were recorded over the 72 hr depuration period. Fluorescence was measured at 3 dpf, after the 24 h exposure, and subsequently at two depuration time points (after a further 24 hr and 72 h): (A) TNF modified AuNP (B) PEG modified AuNP. Raw data are represented as individual fish with means shown (as red lines) for two independent experiments n = 12. (Friedman test, followed by a Dunnett’s post hoc test; ****P < 0.0001, ***P < 0.001 and **P < 0.01).