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Figure Caption
Fig. 5 MM-201 does not alter bacterial liquid growth curves at therapeutically relevant concentrations of MM-201. Co-treatment with one of a range of MM-201 concentrations (100 fM-100 nM) plus 2 µg/mL gentamicin exhibit similar bacterial growth curves as 2 µg/mL gentamicin alone. MM-201 concentrations of 1 µM and 10 µM exhibit modest attenuation of gentamicin bactericidal activity. N = 3 replicates per treatment.
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Reprinted from Hearing Research, 434, Uribe, P.M., Hudson, A.M., Lockard, G., Jiang, M., Harding, J., Steyger, P.S., Coffin, A.B., Hepatocyte growth factor mimetic confers protection from aminoglycoside-induced hair cell death in vitro, 108786108786, Copyright (2023) with permission from Elsevier. Full text @ Hear. Res.