ZFIN Image: Hagio et al., 2023, Figure 5—figure supplement 1

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Figure 5—figure supplement 1—source data 1. Cardiac arrest induced with channelrhodopsins (ChRs) by light of various intensities.

Latency to cardiac arrest (A) and time to resumption of heartbeats (B) after light stimulation with ChRs. The heart area of 4-dpf Tg larvae expressing GtCCR4-3.0-EYFP, KnChR-3.0-EYFP, CrChR2[T159C]-mCherry, or GtACR1-EYFP was irradiated with light (520 nm for GtCCR4, GtACR1; 470 nm for KnChR, CrChR2) for 100 ms at a strength of 0.5, 0.2, or 0.05 mW/mm². Six consecutive stimulation trials were analyzed for four rhodopsin-expressing larvae of each Tg line. One-way ANOVA with Tukey’s post hoc test (time to resumption of heartbeat GtACR1-EYFP 0.5 mW/mm² vs. 0.05 mW/mm², p=0.0240). *p<0.05, ns: not significant. Means and SEMs are indicated.

Figure 5—figure supplement 1—source data 1.Data for <xref rid='fig5s1' ref-type='fig'>Figure 5—figure supplement 1</xref>, cardiac arrest induced with ChRs by light of various intensities.

Acknowledgments

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