ZFIN Image: Rutkove et al., 2023, Figure 5

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Figure 5

Aged gpr27 KOs exhibit greater myofiber atrophy as compared to aged sibling controls. Representative H&E-stained images depicting epaxial caudal musculature in (A) aged WT (36 months; 85% lifespan) and (B) aged gpr27 KO zebrafish (36 months; 85% lifespan). (C) Zoomed-in image of the yellow box shown in panel (A). (D) Zoomed-in image of the yellow box shown in panel (B). (E) Cross-sectional myofiber area and (F) distribution of the sizes of individual myofibers were quantified in H&E sections obtained from the caudal musculature of aged WT and aged KO animals (n = 15–18). ** p ≤ 0.01, **** p ≤ 0.0001.

Acknowledgments

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