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Figure 2—figure supplement 1. OKR measurements indicate decreased eye movement velocity in vsx mutants.

(a-c). OKR was recorded in wildtype (blue), vsx1∆245 (red), vsx2∆73 (green), and vsxKO double mutants (yellow) at 5dpf in response to different contrast (a), spatial frequency (b) and angular velocity (c). OKR is significantly reduced in vsx1∆245 and vsxKO double mutant larvae in comparison to WT siblings (***p<0.001) using a one-way ANOVA. Note that no differences in OKR were observed between WT and vsx2∆73 single mutant or between vsx1∆245 and vsxKO mutants (p>0.05). In (a-c), vsx1∆245 (red tracks) represents both vsx1∆245-/- and vsx1∆245-/-; vsx2∆73+/-genotypes, while vsx2∆73 (green tracks) represents both vsx2∆73-/- and vsx1∆245+/-; vsx2∆73-/- genotypes. In all panels, data is shown as mean ± SEM. deg: degrees, s: seconds.

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