ZFIN Image: Bastos et al., 2023, Figure 1

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Figure Caption

Figure 1

Peptides PSPD2002 and PSPD2003 potentially interact with receptors of the human and zebrafish immune systems. (A) Calculated interaction free energy (Kcal/mol) for PSPD2002 and PSPD2003 interactions for MHC II, MHC class I, TCRα and TCRβ in Homo sapiens and Danio rerio homologous receptors. (B) Docking analysis highlighting the interaction sites between PSPD2002 (purple) and PSPD2003 (blue), and the MHC II, MHC I, TCRα and TCRβ ligands of Danio rerio. Serial dilutions of the peptides being recognized by anti-Spike SARS-CoV-2 antibody for evaluation of the specificity of PSPD2002, in (C), and PSPD2003, in (D).

Acknowledgments

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