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FIGURE 4
Effects of atrial dilation on functional parameters in 48 hpf zebrafish larvae. (A) End-diastolic area (EDA), (B) heart rate (HR), (C) stroke area (SA), and (D) area cardiac output (COA = HR × SA) immediately before (B1-B3) and at the end of load application (S1-S3). Mean values before and during each stretch were compared by paired two-tailed Student’s T-tests. Significance was indicated by p < 0.05. n = 11 larvae.
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