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Fig. 3 Effects of timing of treatments in altering otic patterning. (A– J) Dorsolateral views (anterior to the left) showing expression of otic markers (indicated on the left) at 24 hpf following shorter duration treatment times (indicated at the top) to determine temporal requirements for altered patterning by Wnt and Fgf. Oval marquees encircle the otic vesicle; mean anteroposterior length (±SD, n ≥ 8) is indicated in the pax2a expression images (A–D).
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Reprinted from Developmental Biology, 492, Tan, A.L., Mohanty, S., Guo, J., Lekven, A.C., Riley, B.B., Pax2a, Sp5a and Sp5l act downstream of Fgf and Wnt to coordinate sensory-neural patterning in the inner ear, 139-153, Copyright (2022) with permission from Elsevier. Full text @ Dev. Biol.