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Figure 4 Involvement of FoxM1 on osteoclast differentiation and oxidative stress. RAW 264.7 cells were cultured for 4 days with M-CSF (30 ng/mL) and RANKL (50 ng/mL) and treated with resveratrol (RES), MitoTEMPO (MT) and doxorubicin (DOX) alone or together. RNA from the cells was obtained, and expression levels for FoxM1 (A), Sod 1 (B) and Nrf 2 (C) were analyzed by qPCR. One-way ANOVA, Tukey’s multiple comparisons test, *—p ≤ 0.05, **—p ≤ 0.01, ***—p ≤ 0.001, ****—p ≤ 0.0001.
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Full text @ Int. J. Mol. Sci.