Figure 1 DEPe-induced neurotoxicity. Significant loss of telencephalic neurons and GFP fluorescence with DEPe exposure (A,B). Dorsal view of 5dpf DMSO- (C) and DEPe-treated (D) vmat2:GFP ZF brains. No significant change in diencephalic neuron numbers (E) or fluorescence (F) with DEPe exposure. **p < 0.01, n = 22, 15 (DMSO, DEPe). Significant loss of islet neurons with DEPe exposure (G) but no significant loss of islet fluorescence (H) with DEPe exposure. Lateral view of 5dpf DMSO-treated (I) and DEPe-treated (J) Tg(isl1[ss]:Gal4-VP16,UAS:eGFP)zf154 tail. *p < 0.05, n = 7, 8 (DMSO, DEPe). Student’s T-test; error bars represent SEM.
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