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Fig. 6
The susceptibility of mutated GI.1 proteases to compound 10d. (A) Dose–response inhibition curves showing the effect of compound 10d on the WT proteases. (B) IC50 values of compound 10d on the WT or mutant GI.1 proteases. (C) Dose–response inhibition curves showing the effect of compound 10d on the WT or mutant GI proteases. Mean values ±SEM are presented, Mann–Whitney test, ** p < 0.01, * p < 0.05.
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