FIGURE 1

FIGURE 1

The effect of pancuronium on locomotor activity of zebrafish larvae. (A) Concentration dependent effects of pancuronium on locomotor activity of zebrafish larvae at 24 and 72 hpf. (*p < 0.05, **p < 0.01, Student’s t-test with bonferroni correction). (B) Superimposed images of spontaneous coiling at 24 hpf (left, control; right, 0.5 mM pancuronium). An inset represents the head-tail angle (θ). Max turn angle and max turn speed of spontaneous coiling at 24 hpf are displayed. (Student’s t-test). (C) Superimposed images of touch response at 72 hpf (left, control; right, 0.5 mM pancuronium). An inset represents the head-turn angle (θ). Traveled distance, max turn angle and max turn speed of touch response at 72 hpf are displayed. (**p < 0.01, paired t-test).