ZFIN Image: Weinstein et al., 2022, Fig. 4

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Figure Caption

Fig. 4

Loss of zrsr2 leads to global gene expression changes in metabolic processes. (A) Heatmap of the differentially expressed genes in zrsr2^hg129/hg129 embryos compared to their WT controls at 3 dpf, with the color key shown below the heatmap. An amount of 455 genes were upregulated, and 917 genes were downregulated in the zrsr2^hg129/hg129 samples (fold change ≥ 2, p < 0.05). (B) Bar graph of the top 5 biological processes enriched among 917 downregulated genes in zrsr2^hg129/hg129 embryos at 3 dpf, with enrichment visualized by −log10 (p-value). Metabolic processes and transport of ions, vitamins, and lipids are among the most significantly enriched pathways among the downregulated genes.

Acknowledgments

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