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Fig. 9
Graphic representation of analysis of mRNA expression by RT-qPCR. (A) p21 expression is significantly higher in nop56−/− larvae between 72 and 120 hpf (p-value < 0.0001.) (B) p53 expression is significantly higher in nop56−/− larvae between 72 and 120 hpf (p-value < 0.0001.) (C) Microinjection of p53 morpholino restored the expression in nop56−/− embryos to levels similar to wild type but not the malformations (data not shown). Statistically significant data in the graphs are indicated with a *.
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