Figure 1

Figure 1

The cloning and sequence analysis of grass carp histone H2A variants. (A) The cloning of gcH2A-11 from the gills of grass carp individual 1 infected with F. columnare. (B) The cloning of gcH2A-13 and gcH2A-14~16 from the gills of grass carp individual 2 and 3 infected with F. columnare, respectively. (C) Sequence alignments of gcH2A-4, gcH2A-11 and gcH2A-13~16. The conventional histone H2A region is underlined. (D) Phylogenetic analysis of grass carp histone H2A variants, and histone H2A from other species including shrimp H2A (GenBank accession number: XM_037921631), human H2A.1 (GenBank accession number: M60752), mouse H2A.1 (GenBank accession number: M33988), rat H2A.2 (GenBank accession number: JX661509), human H2A.2 (GenBank accession number: L19779), tongue sole H2A (GenBank accession number: KU904500) and Arabidopsis H2A (GenBank accession number: AK228272).