ZFIN Image: Hason et al., 2022, FIGURE 5

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Figure Caption

FIGURE 5

Targeted signaling pathways as predicted from in vivo kinase inhibitor screen. For simplicity, we show the predicted human proteins in this figure without the zebrafish paralogs. Proteins, that were targeted by our kinase inhibitor set are depicted in color, non-targeted ones are white. Selected inhibitors with a potent new function are depicted in the schemes as well. Signaling pathways in (A) BRAF^V600E mutant melanoma cells and in (B) cells of chronic myelogenous leukemia (CML) with BCR-ABL translocation. Figure created in bioRENDER.

Acknowledgments

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