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Figure 5

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Figures for Dinarello et al., 2022
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Figure 5

Figure 5. Stat3-dependent genes are differentially expressed in gria30 and grs357 mutant lines. (A) RT-qPCR analysis of socs3a in 6 dpf gr+/+ and gria30/ia30 (A) and in gr+/+ and grs357/s357 (A’) larvae with or without Dex treatment. (B) RT-qPCR analysis of hif1αl in 6 dpf gr+/+ and gria30/ia30 (B) and in gr+/+ and grs357/s357 (B’) larvae with or without Dex treatment. (C) RT-qPCR analysis of ulk2 in 6 dpf gr+/+ and gria30/ia30 (C) and in gr+/+ and grs357/s357 (C’) larvae with or without Dex treatment. (D) RT-qPCR analysis of pnpla3 in 6 dpf gr+/+ and gria30/ia30 (D) and in gr+/+ and grs357/s357 (D’) larvae with or without Dex treatment. (E) RT-qPCR analysis of ddit4 in 6 dpf gr+/+ and gria30/ia30 (E) and in gr+/+ and grs357/s357 (E’) larvae with or without Dex treatment. (F) RT-qPCR analysis of socs3a in 6 dpf mr+/+ and mria32/ia32 larvae with or without Dex treatment. (G) RT-qPCR analysis of hif1αl in 6 dpf mr+/+ and mria32/ia32 larvae with or without Dex treatment. (H) RT-qPCR analysis of ddit4 in 6 dpf mr+/+ and mria32/ia32 larvae with or without Dex treatment. (I) RT-qPCR analysis of ulk2 in 6 dpf mr+/+ and mria32/ia32 larvae with or without Dex treatment. (J) RT-qPCR analysis of pnpla3 in 6 dpf mr+/+ and mria32/ia32 larvae with or without Dex treatment. Statistical analyses were performed with Student’s t test. Mean ± SEM. * p < 0.05; ** p< 0.01; *** p < 0.001; **** p < 0.0001; ns = not significant.

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