ZFIN Image: Dal et al., 2021, Fig. 7.

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Figure Caption

Fig. 7. In vivo efficacy of PM-formulated nNF derivatives against Mm infection in zebrafish embryos assessed by survival analysis. Mm-dsRed-infected zebrafish embryos were treated 1 day post infection with the indicated doses of the PM-formulated nNF derivates C7 (A), C11 (B), C12 (C) (5-50 mg/kg) or PM-formulated RIF (D) (5-20 mg/kg) by intravenous injection, and survival was recorded daily. Uninfected untreated embryos were used as a negative control (ctrl) and Mm-infected untreated embryos as an infection control group. Embryos used in this assay are the same as in the FPC assay (Fig. 6). Results are pooled from at least three independent experiments. na, not applicable. **P<0.01, ***P<0.001 (log-rank test of the Kaplan–Meier estimate of survival).

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Acknowledgments

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