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Figure 1
HNC cells demonstrate the greatest uptake of GNPs in lysosomes. Representative images of cells labelled with 25 µM GNPs. Lysosomes are indicated with hashed outlines. (a) FaDu; (b) HSC-3; (c) Detroit-562; (d) SK-N-AS; (e) Panc1; and (f) A673 cells. Cells were fixed approximately 36 h after GNP-labelling (approximate radiation timepoint) and images were captured by a transmission electron microscope. Imaging was done in triplicate—5 images were captured for each sample, with 3 samples/replicate, and 3 replicates in total. HNC head and neck cancer, GNPs gold nanoparticles.
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