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Figure 2
Modulation of Shh alters frequency of TBI-induced PTS events. (A–C) Percentage of fish that displayed spontaneous seizure events spanning the timeframe from within 1 hpi to 5 dpi with and without Shh modulation. (D–F) Percentage of survival across 5 days of fish who initially survived the primary injury across mi-, mo-, and sTBI with and without Shh modulation. Statistical analyses of the repeated-measures data were performed with the Friedman test, n = 100 fish per control/experimental group, grey box denotes period of cyclopamine administration, # p < 0.05, ## p < 0.01.
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