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Publication: Gong et al., 2021 - Nitazoxanide induced myocardial injury in zebrafish embryos by activating oxidative stress response
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FIGURE 1

NTZ exposure induced developmental abnormalities in zebrafish embryos. Live zebrafish embryos were exposed to vehicle control (0.1% DMSO) or NTZ at various concentrations (0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0 and 8.0 mg/L) at 6 hpf. Statistics of (A) mortality, (B) hatching rate and (C) embryo malformation rate are shown. (D–G) Representative images of embryo morphology at 72 hpf. (H) The body length of the embryo at 72 hpf. (I) The yolk area of the embryo at 72 hpf. Note: n = 50 larvae per group. Scale bar: 500 μm in panels d–g. The data were presented as the mean ±standard deviation. *p < 0.05; **p < 0.01

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