ZFIN Image: Berlingerio et al., 2021, Figure 5

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Figure Caption

Figure 5

Increased apoptosis in PTECs with vacuoles in ctns^−/− zebrafish. (A,B) Representative images of the cleaved caspase-3 immunostaining of tubules of wild-type (A) and ctns^−/− (B) 18-month-old zebrafish. The scale bars represent 50 µm. (C,D) The bottom panels show a higher magnification of the boxed areas in the upper panels. Details of PTECs with cytoplasmic vacuoles (*). The scale bars represent 50 µm. (E,F) Representative images of the cleaved caspase-3 immunostaining of glomerulus of wild-type (E) and ctns^−/− (F) 18-month-old zebrafish. The scale bars represent 50 µm. (G) The quantification of the tubular caspase-3 staining positive area in wild-type and ctns^−/− zebrafish in both genders. Each dot represents one zebrafish, for a total of n = 3 wild-type and n = 3 ctns^−/− 18-month-old zebrafish. Two-way ANOVA with Fisher’s least significant difference (PLSD) test: ** p < 0.01; *** p < 0.001.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.