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FIGURE 4

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ZDB-IMAGE-210828-11
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Figures for Islam et al., 2021
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FIGURE 4

Spermatocytes in smc1bQ198X mutants failed to progress beyond the leptotene stage. Labeling of Sycp3 and telomeres in adult wild-type and mutant testes sections: Sycp3 (green), telomere in situ hybridization (orange), DAPI nuclear stain (blue). (A–H) Leptotene stage spermatocytes are present in both wild-type and mutant spermatocytes, examples circled in white. Bouquet stage cells (circled red) are present in wild type but not in the mutant, however, partial telomere clustering is apparent in some mutant cells [e.g., panel (F), inset]. Insets are zoomed images of the areas boxed in purple. Scale bar is 20 μm.

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