ZFIN Image: Afonin et al., 2021, FIGURE 1

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Figure Caption

FIGURE 1 (A) Structure of the antimicrobial peptide cWFW with colour-highlighted aromatic residues that were individually substituted by the fluorescent label in this study; (B) the fluorescent amino acid FHC used as the label (framed and colored) along with potential alternatives, i.e., reported fluorescent amino acids with the excitation wavelengths higher than 360 nm. Compounds are designated according to original reports, excitation wavelengths (“Ex.”) are stated; (C) excited-state intramolecular proton transfer (ESIPT)-mediated fluorescence, causing dual emission and environmental sensitivity of the chromophore in 3-hydroxychromone-containing labels. N (N*) and T (T*) represent normal and tautomeric forms, respectively, in the ground (excited) state; BPT denotes back proton transfer in the ground state.

Acknowledgments

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