Image
|
Figure Caption
Fig. 3 UoS-5247 and UoS-8052 are cytotoxic at a concentration of 100 μM. (A–H) Representative images from the mid-basal ROI of Texas red phalloidin-stained cultures that were exposed to 100 μM of UoS-962 (A), UoS-3606 (B), UoS-3607 (C), UoS-5247 (D), UoS-7691 (E), UoS-7692 (F), UoS-8052 (G), and UoS-9645 (H) alone for 48 hours. UoS-5247 (D) and UoS-8052 (G) show widespread cell death. Images are representative of n = 2 experiments. UoS-8052 was selectively toxic to OHCs, whereas UoS-5247 killed both inner and outer hair cells. Scale bar: 25 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ JCI Insight