ZFIN Image: Hermanowicz et al., 2021, Figure 2.

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Figure Caption

Figure 2.

Schematic of xenograft assay and analysis of tumour development (a). Site-specific injection (yolk sac) of transfected (red) colon cancer cells (DLD-1 and HT-29) into 48 hpf zebrafish embryos and imaging analysis of tumour growth after 48 h of incubation with MM-129 (50 µM), 5-FU (50 µM), or a combination of these agents (b). Quantification of total fluorescence by colon cancer cells three days after injection (c) n = 8, *p < .05, **p < .01, ***<.001 vs. CON; ^p < .05 vs. MM-129, ^#p < .05, ^##p < .01 vs. 5-FU. Data were presented as mean ± standard deviation (SD), and analysed using one-way analysis of variance (ANOVA). p < .05 was considered statistically significant.

Acknowledgments

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