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FIGURE 3

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ZDB-IMAGE-210113-29
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Figures for Mignani et al., 2020
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FIGURE 3

Assessment of the specificity of the phenotype. (A) Embryos were injected with ATG-MO for gene a alone or together with an equimolar dose of p53-MO. (B) The graph shows the size of the eyes in embryos as in (A). Two biological replicates were performed. ****P < 0.001. (C) Embryos were injected with ATG-MO for gene a alone or together with human C19orf12 mRNA, either WT or MUT, and the morphology analyzed at 48 hpf. The graph shows the percentage distribution of embryos in the different phenotypes (normal, mild, and severe) in the three categories of embryos. At least three experiments were performed and more than 150 embryos of each type were analyzed.

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