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Figure 3—figure supplement 2. <italic>adrb2a</italic> and <italic>pgrmc1</italic> mutations have small effects on baseline sleep:wake parameters.

(A–C’) Sleep and waking activity plots for larvae from pgrmc1+/- in crosses. (A,A’) show representative 48 hr traces for the indicated genotypes. The ribbon represents ± SEM. (B–C’) Sleep and waking activity for each larva for all genotypes are plotted. The error bars represent the mean ± SEM. There is a trend to decreased waking activity in pgrmc1-/- mutants compared to wild-type siblings. p=0.07, Kruskal-Wallis, Tukey-Kramer post-hoc. (D–F’) Sleep and waking activity plots for larvae from adrb2a+/- in crosses. (D,D’) show 48 hr traces for all three genotypes. The ribbon represents ± SEM. (E–F’) Sleep and waking activity for the day and night are plotted for each larva. The error bars represent the mean ± SEM. Compared to both wild type and heterozygous siblings, adrb2a-/- mutants have increased sleep during the day. *p≤0.05, Kruskal-Wallis, Tukey-Kramer post-hoc.

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