ZFIN Image: Green et al., 2020, Fig. s2

Image

Figure Caption

Fig. s2 Schematic summary of hs:dkk1b treatments. Timeline of zebrafish development in hours post fertilization, with gastrulation and segmentation periods indicated for reference. Horizontal lines indicate periods of hs:dkk1b mediated Wnt knockdown. Dashed ends on each line indicate uncertainty regarding the beginning and end of active Wnt suppression during heat shock treatments. Based on the loss-of-function phenotypes shown in Fig. 1, we propose three phases of Wnt-mediated patterning; primary AP patterning, mes/R1, and MHB morphogenesis, as indicated above the time line. Arrows point out the heat shock periods shown in Fig. 1

Acknowledgments

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Reprinted from Developmental Biology, 462(2), Green, D.G., Whitener, A.E., Mohanty, S., Mistretta, B., Gunaratne, P., Yeh, A.T., Lekven, A.C., Wnt signaling regulates neural plate patterning in distinct temporal phases with dynamic transcriptional outputs, 152-164, Copyright (2020) with permission from Elsevier. Full text @ Dev. Biol.