ZFIN Image: Wen et al., 2020, Figure 6

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Figure Caption

Figure 6

Knockdown of MMP-9 reduced the metastatic distance and number of SCC-15 cells and decreased the metastasis rate in the zebrafish xenograft model. (a, b) The bright-field and fluorescent pictures of whole-body, head, distal tail regions of zebrafish injected with SCC-15/LVRU6MP (n = 230; magnification, ×32, ×63) and SCC-15/MMP-9/shRNA cells at 5 dpi (n = 290; magnification, ×32, ×63). (c, e) Knockdown of MMP-9 decreased the invasive average distance and number of disseminated cells or lesions at 5 dpi and inhibited the metastasis rate from 3 dpi to 6 dpi. ^∗P < 0.05 and ^∗∗P < 0.01 as compared with the control. Bar = 0.5 mm.

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