ZFIN Image: Pálfy et al., 2020, Fig 1

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Figure Caption

Fig 1 Chromatin accessibility at regulatory elements increases during zygotic genome activation.

a) Schematic of timepoints and embryonic stages chosen for ATAC-seq. “Early” ZGA genes correspond to genes activated until sphere stage and “late” ZGA genes correspond to genes activated after sphere stage. b) Five clusters of chromatin accessibility over the ATAC-seq time-series. c) TSS-centered heatmaps of ATAC-seq peaks in clusters 1 through 4. d) Heatmaps of ATAC-seq peaks centered on putative enhancer regions in clusters 1 through 4. e) Genome browser snapshots of two genomic regions over the ATAC-seq time-series. Peaks belonging to clusters 1–4 are indicated.

Acknowledgments

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