ZFIN Image: Swire et al., 2019, Figure 1

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Figure Caption

Figure 1—figure supplement 2. Social isolation reduces oligodendrocyte generation in the mPFC.

(A) Distance travelled by mice during 5 min of exploration of the social interaction assay. Grouped 15.48 meters ± 3.326 n = 12 mice, Isolated 16.15 meters ± 3.57 n = 9 mice (mean ± standard deviation). (B) Maximum speed travelled by mice during 5 min of exploration of the social interaction assay. Grouped 0.2433 ± 0.04117 n = 12 mice, Isolated 0.2619 meters ± 0.02792 n = 9 mice (mean ± standard deviation). (C) Quantification of CNP positive cells in medial prefrontal cortex layers II/III: Grouped 7709 ± 378.7 n = 5 mice, Isolated 4738 ± 385.7 n = 4 mice (mean ± standard error). (D) Quantification of CNP positive cells in medial prefrontal cortex layer V: Grouped 18879 ± 1559 n = 9 mice, Isolated 13099 ± 1052 n = 9 mice (mean ± standard error). (E) Mean myelin sheath length formed by oligodendrocytes per mouse. Grouped 46.10 µm ± 2.485 n=seven mice, Isolated 51.48 µm ± 4.08 n=four mice (mean ± standard error). (F) Frequency distribution of myelin sheath lengths.

Acknowledgments

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