Figure 2

Figure 2

The 5mC and 5hmC content of the mouse (A) and zebrafish (B) during development. 5mC and 5hmC content are expressed as % of genomic CpG sites. Solid circles represent the overall genomic CpG 5mC status (Jiang et al., 2013; Amouroux et al., 2016; Okamoto et al., 2016; Guo et al., 2017), with crosses representing the overall genomic CpG 5hmC status (Pastor et al., 2013; Wu and Zhang, 2014; Kamstra et al., 2015; Amouroux et al., 2016). Sex symbols indicate the 5mC content of sperm or oocytes. Blue panels represent the general expression level of TET mRNA at particular stages (Yamaguchi et al., 2012; Ge et al., 2014; Amouroux et al., 2016; Bogdanović et al., 2016). X-axes labels indicate the developmental stage of the embryo, with shared positions being analogous between species.