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Fig. S4
Effects of nuclear export inhibition by leptomycin B. 26 hpf DREKA zebrafish larvae were treated with the nuclear export inhibiting compound leptomycin B at 92 μM for 24 h. (A,C,E) Treated DREKA, (B,D,F) untreated control DREKA. Muscle cells (A,B), neural cells in the hindbrain (C,D), and cranial ganglion cells (E,F) all show increased reporter signal in the nucleus in treated embryos compared to untreated siblings. Scale bars in (A,B,D) are 50 μm, in (C,E,F) 25 μm. Images were recorded on a Leica Sp8 X WLL confocal system using a 25x objective. Images were rendered using Adobe Photoshop CS6.
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